Ten lectures on wavelets Contains lectures delivered at the CBMS conference organized in June 1990 by the Mathematics Dept. at the University of Lowell, Mass
CANDELS: THE COSMIC ASSEMBLY NEAR-INFRARED DEEP EXTRAGALACTIC LEGACY SURVEY
2011
CANDELS: THE COSMIC ASSEMBLY NEAR-INFRARED DEEP EXTRAGALACTIC LEGACY SURVEY—THE HUBBLE SPACE TELESCOPE OBSERVATIONS, IMAGING DATA PRODUCTS, AND MOSAICS
2011
Formation of galaxies and large-scale structure with cold dark matter
Angle-resolved photoemission studies of the cuprate superconductors
2003
Experimental Realization of a Three-Dimensional Topological Insulator, Bi 2 Te 3
2009
Giant bandgap renormalization and excitonic effects in a monolayer transition metal dichalcogenide semiconductor
2014
五维评分
172Jeffrey W. Lynn美国国家标准与技术研究院凝聚态与材料他长期从事中子散射实验,为磁性材料的结构与激发研究提供了重要数据。
综合分 3.72
h 指数 75
美国
授奖措辞
表彰其以中子散射实验揭示铁基超导体中的磁有序,为磁性材料结构与激发研究提供重要数据。
代表作
Magnetic order close to superconductivity in the iron-based layered LaO1-xF x FeAs systems
2008
Magnetic Inversion Symmetry Breaking and Ferroelectricity inTbMnO3
2005
Neutron-Diffraction Measurements of Magnetic Order and a Structural Transition in the ParentBaFe2As2Compound of FeAs-Based High-Temperature Superconductors
2008
五维评分
173Virgil Bruce Elings粒子与高能商用原子力显微镜的推动者。他让纳米尺度的成像成为普通实验室的常规手段。
综合分 3.69
h 指数 47
授奖措辞
表彰其推动商用原子力显微镜与轻敲模式成像,使纳米尺度成像成为普通实验室的常规手段。
代表作
Phase imaging and stiffness in tapping-mode atomic force microscopy
1997
Fractured polymer/silica fiber surface studied by tapping mode atomic force microscopy
1993
Tapping mode atomic force microscopy in liquids
1994
五维评分
第 17 / 23 页
序号学者研究领域主要贡献
174BAB. P. Abbott天体与宇宙大型引力波合作组的成员,是这一集体性科学成果的署名者之一。
综合分 3.67
h 指数 62
授奖措辞
表彰其作为 LIGO 合作组成员,参与首次观测双黑洞并合引力波的历史性成果。
代表作
Observation of Gravitational Waves from a Binary Black Hole Merger
2016
Gravitational Waves and Gamma-Rays from a Binary Neutron Star Merger: GW170817 and GRB 170817A
Diffraction contrast of electron microscope images of crystal lattice defects - II. The development of a dynamical theory
1961
Diffraction contrast of electron microscope images of crystal lattice defects. III. Results and experimental confirmation of the dynamical theory of dislocation image contrast
1962
Anomalous electron absorption effects in metal foils: theory and comparison with experiment
QUANTUM ESPRESSO: a modular and open-source software project for quantum simulations of materials
2009
Unified Approach for Molecular Dynamics and Density-Functional Theory
1985
Deep Potential Molecular Dynamics: A Scalable Model with the Accuracy of Quantum Mechanics
2018
五维评分
41Harry B. Gray加州理工学院生物化学与结构生物无机化学的奠基人。他阐明了金属蛋白中的电子如何完成长距离传递。
综合分 6.64
91 岁 · h 指数 123
美国
前哨奖项
Wolf Prize in Chemistry(2004)
授奖措辞
表彰其对生物无机化学的奠基性贡献,阐明了金属蛋白中的长距离电子传递。
代表作
Powering the planet with solar fuel
2009
Earth-Abundant Heterogeneous Water Oxidation Catalysts
2016
The Electronic Structure of the Vanadyl Ion
1962
五维评分
42Dennis Lo Yuk-Ming香港中文大学生物化学与结构无创产前检测与液体活检的开创者。他发现孕妇血液中含有胎儿的 DNA,让产前筛查变成一次简单的抽血。
综合分 6.63
63 岁 · h 指数 103
中国
授奖措辞
表彰其发现孕妇血浆中的胎儿DNA,开创了无创产前检测与液体活检。
代表作
Presence of fetal DNA in maternal plasma and serum
1997
Quantitative Analysis of Fetal DNA in Maternal Plasma and Serum: Implications for Noninvasive Prenatal Diagnosis
1998
Rapid Clearance of Fetal DNA from Maternal Plasma
1999
五维评分
43David Klenerman剑桥大学生物化学与结构新一代 DNA 测序技术的共同发明人。他让大规模并行测序从概念变成可靠的工具。
综合分 6.63
67 岁 · h 指数 83
英国
授奖措辞
表彰其共同发明可逆终止子测序技术,使大规模并行测序从概念变为可靠的工具。
代表作
Accurate whole human genome sequencing using reversible terminator chemistry
2008
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
2018
Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
2012
五维评分
第 4 / 14 页
序号学者研究领域主要贡献
44Galen D. Stucky加州大学圣塔芭芭拉分校有机合成与催化介孔材料的共同开创者。他参与发展了有序介孔分子筛的合成体系。
综合分 6.57
90 岁 · h 指数 152
美国
前哨奖项
Clarivate Citation Laureate(2014)
授奖措辞
表彰其设计功能性介孔材料。
代表作
Triblock Copolymer Syntheses of Mesoporous Silica with Periodic 50 to 300 Angstrom Pores
1998
Nonionic Triblock and Star Diblock Copolymer and Oligomeric Surfactant Syntheses of Highly Ordered, Hydrothermally Stable, Mesoporous Silica Structures
1998
Surfactant Control of Phases in the Synthesis of Mesoporous Silica-Based Materials
Electrical Energy Storage for the Grid: A Battery of Choices
2011
Li–O2 and Li–S batteries with high energy storage
2011
Nanostructured materials for advanced energy conversion and storage devices
2005
五维评分
56Samuel J. Danishefsky哥伦比亚大学有机合成与催化全合成的泰斗。他在复杂天然产物与糖类分子的合成上有长期而杰出的工作。
综合分 6.17
90 岁 · h 指数 113
美国
前哨奖项
Wolf Prize in Chemistry(1995)Clarivate Citation Laureate(2007)
授奖措辞
表彰其在合成多种复杂有机化合物方面的研究,如埃坡霉素与加利车霉素,这些天然产物有望成为抗癌药物。
代表作
The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis
2001
Free‐Radical‐Based, Specific Desulfurization of Cysteine: A Powerful Advance in the Synthesis of Polypeptides and Glycopolypeptides
2007
Glycals in Organic Synthesis: The Evolution of Comprehensive Strategies for the Assembly of Oligosaccharides and Glycoconjugates of Biological Consequence
Synthesis, Structure, and Properties of Boron‐ and Nitrogen‐Doped Graphene
2009
MoS2 and WS2 Analogues of Graphene
2010
五维评分
63Ralph G. Nuzzo伊利诺伊大学厄巴纳-香槟分校材料与高分子自组装单分子层的共同奠基者。他与合作者首次让整齐的分子单层牢固结合在裸金属表面,并由此发展出软刻蚀等廉价微纳加工方法,深刻影响了表面科学与微电子制造。
综合分 5.86
72 岁 · h 指数 95
授奖措辞
表彰其关于硫醇分子在金属表面自组装单分子层的奠基性工作,及其对表面科学与软刻蚀的深远影响。
代表作
Self-Assembled Monolayers of Thiolates on Metals as a Form of Nanotechnology
2005
Formation of monolayer films by the spontaneous assembly of organic thiols from solution onto gold
1989
Comparison of the structures and wetting properties of self-assembled monolayers of n-alkanethiols on the coinage metal surfaces, copper, silver, and gold
1991
五维评分
第 6 / 14 页
序号学者研究领域主要贡献
64Alexander D. MacKerell马里兰大学巴尔的摩分校生物化学与结构生物分子力场的核心开发者。他参与建立的模拟工具被全世界生物化学研究者广泛使用。
综合分 5.85
h 指数 107
美国
授奖措辞
表彰其建立蛋白质全原子经验力场,为生命科学领域的分子模拟与动力学研究提供了核心工具。
代表作
All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins
1998
五维评分
65Clifford P. Brangwynne普林斯顿大学生物化学与结构相分离领域的共同开创者。他发现细胞内的蛋白质可以像油滴一样自发聚集。
综合分 5.75
48 岁 · h 指数 61
美国
前哨奖项
Clarivate Citation Laureate(2025)
授奖措辞
表彰其发现相分离生物分子凝聚体在细胞生化组织中的作用。
代表作
Liquid phase condensation in cell physiology and disease
2017
Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
Synthesis of Highly Ordered Carbon Molecular Sieves via Template-Mediated Structural Transformation
1999
Ordered Mesoporous Carbons
2001
Cubic Ia3d large mesoporous silica: synthesis and replication to platinum nanowires, carbon nanorods and carbon nanotubesElectronic supplementary information (ESI) available: TEM images of mesoporous cubic silica and Pt networks, XRD patterns during formation of the cubic phase. See http://www.rsc.org/suppdata/cc/b3/b306504a/
2003
五维评分
75Ching Wan Tang罗切斯特大学有机合成与催化有机发光二极管的发明人。他让有机材料第一次能高效地把电变成光,如今成为显示与照明的主流技术。
综合分 5.38
79 岁 · h 指数 21
美国
前哨奖项
Wolf Prize in Chemistry(2011)Clarivate Citation Laureate(2014)
授奖措辞
表彰其发明有机发光二极管。
代表作
Anthracene derivatives for stable blue-emitting organic electroluminescence devices
2002
Organic Electroluminescent Materials and Devices
1996
Bulk Heterojunction Photovoltaic Cells with Low Donor Concentration
Polymerization of Methyl Methacrylate with the Carbon Tetrachloride/Dichlorotris- (triphenylphosphine)ruthenium(II)/Methylaluminum Bis(2,6-di-tert-butylphenoxide) Initiating System: Possibility of Living Radical Polymerization
1995
Sequence-Controlled Polymers
2013
五维评分
78Michael K. Rosen德克萨斯大学生物化学与结构液-液相分离范式的奠基人之一。他证明细胞内的蛋白质凝聚体是理解细胞内组织方式的关键。
综合分 5.38
61 岁 · h 指数 78
美国
前哨奖项
Clarivate Citation Laureate(2025)
授奖措辞
表彰其发现相分离生物分子凝聚体在细胞生化组织中的作用。
代表作
Biomolecular condensates: organizers of cellular biochemistry
2017
Phase transitions in the assembly of multivalent signalling proteins
2012
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
Novel Cavity Design Using Calix[n]arene Skeletons: Toward Molecular Recognition and Metal Binding
1997
Saccharide Sensing with Molecular Receptors Based on Boronic Acid
1996
Organic Templates for the Generation of Inorganic Materials
2003
五维评分
82Karen L. Wooley德克萨斯农工大学有机合成与催化聚合物纳米医学的贡献者。她设计了可在体内降解的纳米载体,用于药物递送与成像。
综合分 5.30
60 岁 · h 指数 99
美国
前哨奖项
Clarivate Citation Laureate(2023)
授奖措辞
表彰其开发创新的药物与基因靶向及递送方法。
代表作
Design of polymeric nanoparticles for biomedical delivery applications
2012
Applications of Orthogonal “Click” Chemistries in the Synthesis of Functional Soft Materials
2009
The Convergence of Synthetic Organic and Polymer Chemistries
2005
五维评分
83Henri B. Kagan巴黎第十一大学有机合成与催化不对称催化的先驱。他最早证明手性配体可以让反应只生成一种构型的产物。
综合分 5.26
h 指数 77
法国
前哨奖项
Wolf Prize in Chemistry(2001)
授奖措辞
表彰其作为不对称催化先驱的贡献,率先用手性膦铑配合物实现对映选择性还原并发展动力学拆分方法。
代表作
Divalent lanthanide derivatives in organic synthesis. 1. Mild preparation of samarium iodide and ytterbium iodide and their use as reducing or coupling agents
1980
Asymmetric catalytic reduction with transition metal complexes. I. Catalytic system of rhodium(I) with (-)-2,3-0-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane, a new chiral diphosphine
Living Free-Radical Polymerization by Reversible Addition−Fragmentation Chain Transfer: The RAFT Process
1998
Living Radical Polymerization by the RAFT Process
2005
Living Radical Polymerization by the RAFT Process – A Third Update
2012
五维评分
89Jay R. Winkler加州理工学院物理化学与理论阐明蛋白质内部电子如何长距离传递的代表性学者。他揭示了电子在蛋白质中的隧穿路径与机理,深化了人们对光合作用与生物能量转换的理解。
综合分 5.14
61 岁 · h 指数 80
授奖措辞
表彰其阐明蛋白质内部电子的长程隧穿路径与机理,深化了对光合作用与生物能量转换的理解。
代表作
ELECTRON TRANSFER IN PROTEINS
1996
Long-range electron transfer
2005
Electron tunneling through proteins
2003
五维评分
90Michael Hunkapiller太平洋生物科学公司生物化学与结构自动化 DNA 测序仪的共同发明人,并把这一技术推向了产业化。
综合分 5.13
78 岁 · h 指数 53
美国
前哨奖项
Clarivate Citation Laureate(2019)
授奖措辞
表彰其对蛋白质与 DNA 测序和合成的贡献。
代表作
The Sequence of the Human Genome
2001
The complete sequence of a human genome
2022
A gas-liquid solid phase peptide and protein sequenator.
1981
五维评分
91Helmut F. Schwarz柏林工业大学有机合成与催化气相离子化学的专家。他在孤立离子的反应机理研究上有系统贡献。
综合分 5.12
83 岁 · h 指数 99
德国
前哨奖项
BBVA Frontiers(2024)Wolf Prize in Chemistry(2025)
授奖措辞
表彰其系统研究气相离子化学,提出有机金属反应中的两态反应性等新概念,阐明孤立离子的反应机理。
代表作
Two-State Reactivity as a New Concept in Organometallic Chemistry
2000
The singlet and triplet states of phenyl cation. A hybrid approach for locating minimum energy crossing points between non-interacting potential energy surfaces
1998
Gas‐Phase Catalysis by Atomic and Cluster Metal Ions: The Ultimate Single‐Site Catalysts
Living Free-Radical Polymerization by Reversible Addition−Fragmentation Chain Transfer: The RAFT Process
1998
Living Radical Polymerization by the RAFT Process
2005
Living Radical Polymerization by the RAFT Process – A Third Update
2012
五维评分
第 9 / 14 页
序号学者研究领域主要贡献
94David L. Allara宾夕法尼亚州立大学材料与高分子自组装单分子层的奠基者之一。他与合作者证明,长链分子能在金属表面自发排成整齐的单层,从此人们可以对材料表面进行分子尺度的精确修饰,这一方法被广泛用于传感器与半导体制造。
综合分 5.08
89 岁 · h 指数 75
授奖措辞
表彰其关于有机分子在金属表面自发有序组装的奠基性研究,使材料表面的分子尺度精确修饰成为可能。
代表作
Spontaneously organized molecular assemblies. 4. Structural characterization of n-alkyl thiol monolayers on gold by optical ellipsometry, infrared spectroscopy, and electrochemistry
1987
Comparison of the structures and wetting properties of self-assembled monolayers of n-alkanethiols on the coinage metal surfaces, copper, silver, and gold
1991
Fundamental studies of microscopic wetting on organic surfaces. 1. Formation and structural characterization of a self-consistent series of polyfunctional organic monolayers
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.
1986
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
2000
Preparation and Biological Characterization of Polymeric Micelle Drug Carriers with Intracellular pH-Triggered Drug Release Property: Tumor Permeability, Controlled Subcellular Drug Distribution, and Enhanced in Vivo Antitumor Efficacy
2004
五维评分
105Edwin Southern牛津大学生物化学与结构以他命名的印迹技术让特定的 DNA 片段可以在混合物中被找到,是分子生物学的经典工具。
综合分 4.63
88 岁 · h 指数 26
英国
前哨奖项
Clarivate Citation Laureate(2019)
授奖措辞
表彰其发明用于测定特定DNA序列的Southern印迹法。
代表作
Molecular interactions on microarrays
1999
[9] Gel electrophoresis of restriction fragments
1979
Use of restriction enzymes to study eukaryotic DNA methylation
1978
五维评分
106Hartmuth C. Kolb美国强生公司有机合成与催化点击化学概念的共同提出者之一,推动了这一反应体系在多个领域的普及。
综合分 4.60
h 指数 64
美国
授奖措辞
表彰其作为点击化学概念的共同提出者,推动这一模块化反应体系在化学与生命科学多个领域的普及。
代表作
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001
五维评分
107Vladimir P. Torchilin东北大学(波士顿)生物化学与结构纳米药物递送领域的重要研究者,在脂质体与聚合物载体上有长期工作。
Organized monolayers by adsorption. 1. Formation and structure of oleophobic mixed monolayers on solid surfaces
1980
On the formation and structure of self-assembling monolayers. I. A comparative atr-wettability study of Langmuir—Blodgett and adsorbed films on flat substrates and glass microbeads
1984
Organized self-assembling monolayers on electrodes
1987
五维评分
109Raphael David Levine加州大学洛杉矶分校物理化学与理论化学动力学理论的重要学者。他在分子反应速率与激光化学的理论描述上有经典贡献。
综合分 4.49
88 岁 · h 指数 70
美国
前哨奖项
Wolf Prize in Chemistry(1988)
授奖措辞
表彰其对分子反应动力学理论的经典贡献,包括最大熵形式与分子振转光谱的代数描述方法。
代表作
Molecular Reaction Dynamics and Chemical Reactivity
1988
The Maximum Entropy Formalism
1979
Algebraic approach to molecular rotation-vibration spectra. I. Diatomic molecules
Long-Range Charge Transfer in DNA: Transient Structural Distortions Control the Distance Dependence
2000
Long-distance charge transport in duplex DNA: The phonon-assisted polaron-like hopping mechanism
1999
Chemiluminescence of organic peroxides. Conversion of ground-state reactants to excited-state products by the chemically initiated electron-exchange luminescence mechanism
Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia
2001
Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification
2001
Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome
Mammalian Transcription Factor ATF6 Is Synthesized as a Transmembrane Protein and Activated by Proteolysis in Response to Endoplasmic Reticulum Stress
1999
Identification of the cis-Acting Endoplasmic Reticulum Stress Response Element Responsible for Transcriptional Induction of Mammalian Glucose-regulated Proteins
1998
ATF6 Activated by Proteolysis Binds in the Presence of NF-Y (CBF) Directly to thecis-Acting Element Responsible for the Mammalian Unfolded Protein Response
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples
1977
Mortality in relation to smoking: 40 years' observations on male British doctors
1994
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials
T cell tolerance by clonal elimination in the thymus
1987
The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice
1989
Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity
Completion of mouse embryogenesis requires both the maternal and paternal genomes
1984
Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1).
1978
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
2014
五维评分
75Ravinder N. Maini牛津大学免疫学抗 TNF 疗法的共同开创者,他让自身免疫疾病第一次有了针对性治疗。
综合分 6.53
89 岁 · h 指数 86
英国
前哨奖项
Lasker(2003)Gairdner(2014)
授奖措辞
表彰其共同开创抗TNF抗体疗法,使类风湿关节炎首次获得针对性治疗。
代表作
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis
2000
ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS
1996
Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial
1999
五维评分
76Karl J. Friston伦敦大学学院神经科学脑成像分析方法的巨擘。他建立的统计方法让脑功能图像第一次可以被严谨地解读。
综合分 6.51
67 岁 · h 指数 262
英国
前哨奖项
Clarivate Citation Laureate(2017)
授奖措辞
表彰其对脑成像数据分析的基础性贡献,尤其是通过统计参数映射与基于体素的形态学测量所做出的贡献。
代表作
Statistical parametric maps in functional imaging: A general linear approach
1994
Voxel-Based Morphometry—The Methods
2000
The free-energy principle: a unified brain theory?
2010
五维评分
77Lynne Elizabeth Maquat罗切斯特大学分子与细胞生物学她发现了细胞清理缺陷遗传信息的机制,深化了对基因表达质量控制的理解。
综合分 6.51
74 岁 · h 指数 82
美国
前哨奖项
Gairdner(2015)Wolf Prize(2021)
授奖措辞
表彰其发现无义介导的mRNA降解机制,深化了对基因表达质量控制的理解。
代表作
lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′ UTRs via Alu elements
2011
Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics
2004
A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance
1998
五维评分
78Steven A. Rosenberg美国国家癌症研究所分子与细胞生物学肿瘤免疫治疗的奠基人。他最早证明改造后的免疫细胞可以攻击肿瘤。
综合分 6.49
86 岁 · h 指数 219
美国
前哨奖项
Clarivate Citation Laureate(2023)
授奖措辞
表彰其在推动嵌合抗原受体 T 细胞疗法用于癌症治疗方面的突破性研究。
代表作
A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone
1987
A Randomized Trial of Bevacizumab, an Anti–Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer
2003
Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic Cancer
Liposomal drug delivery systems: From concept to clinical applications
2012
Drug Delivery Systems: Entering the Mainstream
2004
Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential
1985
五维评分
85Gordon J. Freeman哈佛医学院免疫学他发现了肿瘤用来躲避免疫攻击的关键分子,为免疫治疗提供了重要靶点。
综合分 6.38
76 岁 · h 指数 175
美国
前哨奖项
Clarivate Citation Laureate(2016)
授奖措辞
表彰其阐明程序性细胞死亡蛋白-1(PD-1)及其通路,推动了癌症免疫治疗。
代表作
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
2018
PD-1 and Its Ligands in Tolerance and Immunity
2008
PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma
2014
五维评分
86Bruce M. Alberts美国加利福尼亚州旧金山分子与细胞生物学DNA 复制机制的重要研究者,同时长期推动科学教育,影响了几代学生。
综合分 6.38
88 岁 · h 指数 87
美国
前哨奖项
Gairdner(1995)Lasker(2016)
授奖措辞
表彰其在DNA复制与细胞蛋白机器研究上的贡献,以及《细胞分子生物学》对几代学者的深远影响。
代表作
Molecular Biology of the Cell
2017
Molecular Biology of the Cell
2007
The Cell as a Collection of Protein Machines: Preparing the Next Generation of Molecular Biologists
1998
五维评分
87Jack L. Strominger哈佛大学免疫学免疫分子结构与功能的经典贡献者。他揭示了免疫系统如何呈递抗原。
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
1987
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain
1987
五维评分
106Lewis E. Kay多伦多大学分子与细胞生物学核磁共振结构生物学的方法大师,他发展的技术让蛋白质的动态结构可以被细致观察。
综合分 5.94
65 岁 · h 指数 109
加拿大
前哨奖项
Gairdner(2017)
授奖措辞
表彰其发展核磁共振弛豫方法,使蛋白质主链动态结构得以细致观察。
代表作
Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation
1994
Backbone dynamics of calmodulin studied by nitrogen-15 relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible
1992
New Tools Provide New Insights in NMR Studies of Protein Dynamics
UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
2015
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies
2002
Blood pressure, stroke, and coronary heart disease
1990
五维评分
135Robert L. CoffmanDynavax 技术公司分子与细胞生物学他提出的免疫应答分型假说奠定了人们对不同类型免疫反应的理解。
综合分 5.51
78 岁 · h 指数 113
美国
前哨奖项
Clarivate Citation Laureate(2011)
授奖措辞
表彰其发现两类 T 淋巴细胞 TH1 与 TH2,及其在调控宿主免疫应答中的作用。
代表作
TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties
1989
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999
Ghrelin: Structure and Function
2005
Ghrelin, a Novel Growth Hormone-Releasing Acylated Peptide, Is Synthesized in a Distinct Endocrine Cell Type in the Gastrointestinal Tracts of Rats and Humans1
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.
1994
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
1985
Identification of the NF-E2-related Factor-2-dependent Genes Conferring Protection against Oxidative Stress in Primary Cortical Astrocytes Using Oligonucleotide Microarray Analysis
2003
五维评分
183Michael S. Waterman美国加利福尼亚州洛杉矶南加州大学生物科学、数学与计算机科学教授遗传与基因组计算生物学的奠基人之一,他让序列比对成为基因组研究的通用方法。
综合分 4.77
h 指数 72
前哨奖项
Gairdner(2002)
授奖措辞
表彰其在计算生物学方面的奠基性贡献,包括成为基因组研究通用方法的序列比对算法。
代表作
Identification of common molecular subsequences
1981
The B73 Maize Genome: Complexity, Diversity, and Dynamics
2009
An Eulerian path approach to DNA fragment assembly
Molecular aspects of bacterial pH sensing and homeostasis
2011
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
Identification of the Cystic Fibrosis Gene: Chromosome Walking and Jumping
1989
Mutations in the human Sonic Hedgehog gene cause holoprosencephaly
1996
The Relation between Genotype and Phenotype in Cystic Fibrosis — Analysis of the Most Common Mutation (ΔF508)
1990
五维评分
198John B. Glen帝国化学工业公司神经科学他发明了丙泊酚,这种起效快、恢复快的麻醉药至今仍在全球广泛使用。
综合分 4.51
h 指数 24
英国
前哨奖项
Lasker(2018)
授奖措辞
表彰其发明丙泊酚,这种起效快、恢复快的麻醉药至今在全球临床广泛使用。
代表作
Selective digestive or oropharyngeal decontamination and topical oropharyngeal chlorhexidine for prevention of death in general intensive care: systematic review and network meta-analysis
2014
Pharmacokinetic Model Selection for Target Controlled Infusions of Propofol
1995
ANIMAL STUDIES OF THE ANAESTHETIC ACTIVITY OF ICI 35 868
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies
2002
五维评分
第 23 / 26 页
序号学者研究领域主要贡献
234DGDavid A. Guertin麻省大学纪念医疗中心癌症与肿瘤他参与了细胞生长调控复合体的发现,是这一方向的合作贡献者。
综合分 3.44
h 指数 44
美国
授奖措辞
表彰其发现Rictor-mTOR复合体,阐明mTOR复合体2磷酸化并调控Akt的细胞生长机制。
代表作
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
2005
五维评分
235Lijun Sun肯塔基大学免疫学他参与了细胞察觉外来 DNA 机制中关键分子的发现,是这一工作的合作者。
综合分 3.40
h 指数 35
美国
授奖措辞
表彰其发现环鸟苷酸-腺苷酸合成酶,揭示细胞质识别外源DNA并激活I型干扰素通路的关键机制。
代表作
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012
五维评分
236Linda K. Kwong老龄化研究所分子与细胞生物学她参与了神经退行性疾病关键病理蛋白的发现工作,是这一团队的重要成员。
综合分 3.33
h 指数 47
美国
授奖措辞
表彰其发现泛素化TDP-43为额颞叶变性与肌萎缩侧索硬化症的关键病理蛋白。
代表作
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis